Hannibal Unemployment Office
Where to go in person in Hannibal, Missouri: the American Job Center in the city, and 1 more within 25 miles. Staff there help with finding work, training and your next steps.
✓ From the U.S. Department of Labor's list ✓ Address, phone and hours
About your claim
Regional Claims Center, outside local calling area
Call 800-320-2519Jobareer is not the state. This is DES's number, from its own website.
The office in Hannibal
Missouri Job Center - Hannibal
Full-service American Job Center
203 North Sixth Street
Hannibal, MO 63401 · Directions
Phone: 573-248-2520
Hours: Monday - Thursday 8am - 5pm; Friday 9:00 am - 4:00 pm
Listed by the U.S. Department of Labor, updated October 20, 2026.
Near Hannibal
Quincy Workforce Service Center
Full-service American Job Center · 15 miles away
107 N. 3rd St.
Quincy, IL 62301 · Directions
Phone: 217-224-8171
Hours: Closed to the public; open by appointment
Listed by the U.S. Department of Labor, updated October 26, 2026.
Can I file for unemployment at these offices?
These are American Job Centers, a network funded by the U.S. Department of Labor and run locally. Whether you can file or fix a claim there depends on the state. Here is what DES says about filing:
"File online in UInteract: create a user ID and password with New Account Registration, then log in and choose Unemployment Claim, then File Unemployment Claim, and follow the prompts."
From the agency's own page, read October 14, 2026. File a claim on the agency's site.
Before you go
Hours change, and some centers see people by appointment. Call the center before you go. More about unemployment in Missouri: how to file, the weekly claim and how much it pays, and every phone number.
Where this comes from
The centers, their addresses, phones and hours are from the U.S. Department of Labor's American Job Center finder (CareerOneStop), as each center last updated it. Jobareer is not part of any state agency and cannot see or change your claim.
If your state asks you to look for work each week
Our free job application tracker keeps the list your state may ask for: where you applied, when, and what came of it.